Some Hematological Parameters among Patients with Pulmonary Tuberculosis – Khartoum State

Tuberculosis is a highly prevalent chronic infectious disease caused and it’s still a common disease in develop countries and still a major cause of mortality today , can affect many part of the body like lung and bone this defect can lead to defect in most of blood component. The aim of the study is to measure some of hematological parameters among Sudanese patients affected with pulmonary tuberculosis in Khartoum state. During the period between April to August 2013. 40 patients with pulmonary tuberculosis (25 males and 15 females) and 20 healthy controls (14 males and 6 females) were included 2.5 ml of blood was collected from patients and controls into EDTA containers then CBC Test was carried out immediately after collection, were carried out (Hb, RBCs count, HCT, MCV, MCH, MCHC, TWBCs, platelet count and differential leucocyte count) using Hematological analyzer (Sysmex KX21N). Data obtained were analyzed using software program statistical package of social science (SPSS.V.11.5).The results in pulmonary tuberculosis patients when compared with control showed that there was significant lower values in Hemoglobin (Hb), Red Cell Count (RBCs) and Packed Cell Volume (PCV) (P= 0.00) and normal Means MCV (83.4±2), Mean MCH (30.1±4.3) and MCHC (36.1±1.1) in T.B patients compared with controls group. Total leukocyte count (TWBCs) and absolute Monocyte count was found both significant increase (P=0.00) compared to controls. The absolute Neutrophil count showed significant increase in T.B patients (P. 0.008) compared with control. And the most type of anemia was normocytic normochromic anemia. The significant increase in platelet count (Thrombocytosis) was showed in T.B patients (P. 0.00) compared with controls group. Moderate normocytic normochromic anemia , leuckocytosis especially neutrophilia with monocytosis and moderate thrombocytosis was found in T.B patients compared to controls group and other further studied is needed in this field.